Sunday, August 11, 2013

Qivana's Prime Nitric Oxide Activator


prime-overview

The “Miracle Molecule” that Combats Aging.Most of us are willing to accept that many things just come along with aging – heart disease, poor memory, lack of energy, cold hands/feet, slower cognition, and sexual problems.The truth is that an incredible molecule, known as Nitric Oxide, can help restore many of these vital functions and processes. It’s presence in our body improves blood flow crucial to the healthy function of nearly every organ and tissue in the body. In fact, the discovery of Nitric Oxide’s role in cardiovascular was so revolutionary that it was awarded a Nobel Prize in Medicine in 1998. However, after age 40, most of us fail to produce enough nitric oxide..that’s where PRIME comes in. PRIME is the most efficient and effective way to restore Nitric Oxide and improve blood flow.


prime edge
PRIME is the most effective method available for restoring Nitric Oxide and improving blood flow. Most supplement companies don’t bother with research, but PRIME was more than 10 years in development with the top Nitric Oxide scientists in the world. This is truly a next-generation product. All of the Nitric-Oxide products on the market rely entirely on the amino acid L-arginine to boost nitric oxide. Yet this complex pathway has proven to be highly inefficient and works much less in people over age 40. L-arginine supplements can help some, but we’ve proven they aren’t the best. PRIME is so advanced that it’s light years ahead of the next best product on the market. It is the only product that restores Nitric Oxide production using all the known pathways, not just L-arginine. We’ve tested hundreds and hundreds of different plants, roots, barks, foods, and extracts. Using our proprietary algorithm we were able to quantify the Nitric Oxide potential of each and create a supplement using only the most potent materials proven to produce nitric oxide. We don’t ignore the L-arginine pathway…but we also use entirely new and different pathways, that are more effective for creating nitric oxide. Our technology also takes advantage of a little known fact – a significant amount of N-O production occurs in the mouth! That’s right…nutrients react with bacteria in the mouth and produce nitric oxide. That means that the majority of the products can’t take advantage of this pathway because they bypass the mouth entirely using capsules, tablets, pills, and even drinks. Our Direct Dissolve® powder formula is specifically designed to sit in your mouth and begin producing nitric oxide immediately. PRIME is light-years ahead of the competition.


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 Our arteries are the transportation highway for oxygen and nutrient rich blood to reach every organ, tissue, and cell in our body. And Nitric-Oxide (N-O) is the nutrient that keeps this highway wide-open, flexible, and smooth for blood to flow freely. At age 40, we experience a natural but dramatic decline in Nitric Oxide production. Without intervention, our arteries tend to narrow and stiffen, creating a buildup of plaque, compromising blood flow. PRIME gives you a daily shot of powerful nutrients proven to promote N-O production and maximize blood flow.

More Info:
 Promotes vasodilation (expansion of arteries and blood vessels) critical for maintaining healthy blood pressure levels, that are already in a normal range Maximizes circulation – signals the arterial smooth muscle to relax, dilating blood vessels, and improving blood flow Prevents premature cardiovascular aging by promoting blood vessel flexibility and health Encourages normal sexual function in both men and women by enhancing blood flow to penile and vaginal tissues Promotes neuronal communication and blood flow to the brain, which encourages clear thinking, faster cognition, and enhanced memory recall Improved blood flow leads to improvements in energy, mood, and general feelings of well-being
 Take 1 PRIME packet first thing in the morning on an empty stomach and before brushing. PRIME should be taken at least 30 minutes prior to eating. For best results take 2 packets consistently for 90 days, followed by 1 packet per day for maintenance. Take once or twice daily, 12 hours apart. Pour a small amount of powder on your tongue and allow to dissolve before swallowing. Repeat until finished. In the first month of use, two packets per day are recommended for optimal results. Prepare to live life 10 years younger! NOTE: Those who are pregnant, breastfeeding, or who have a known medical condition, should consult a physician prior to taking a new supplement. Store in a cool, dry, place.

Other Ingredients: Fructose (natural sweetener), Natural Flavors and Citric Acid.


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PRIME N-O ACTIVATOR


Scientific Research:

 • Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, et al. Heart disease and stroke statistics –2012 update: A report from the American Heart Association. Circulation. 2012 Jan; 125(1): e2-e220

 • Marsh N, Marsh A. A short history of nitroglycerin and Nitric Oxide in pharmacology and physiology. Clin Exp Pharmacol Physiol. 2000 Apr; 27(4): 313-9. • Palmer RMJ, Ferrige AG, Moncada S. Nitric Oxide release accounts for the biological activity of endothelium derived relaxing factor. Nature. 1987 June; 327(11): 524-526.

 • Loscalzo J, Welch G. Nitric Oxide and its role in the cardiovascular system. Prog Cardiovasc Dis.1995 Sept; 38(2): 87-104.

 • Zand J, Lanza F, Garg HK, Bryan NS. All-natural nitrite and nitrate containing dietary supplement promotes Nitric Oxide production and reduces triglycerides in humans. Nutr Res. 2011; 31: 262-269. • Bryan NS. Application of Nitric Oxide in drug discovery and development.Expert Opinions in Drug Discovery. 2011 Nov; 6(11): 1139-54.

 • World Health Organization. Cardiovascular diseases fact sheet; 2011.

 • Bondonno CP, Croft KD, Puddey IB, Considine MJ, Yang X, Ward NC, Hodgson JM. Nitrate causes a dose dependent augmentation of Nitric Oxide status in healthy women. Food Funct. 2012 Feb.

 • Serafim RA, Primi MC, Trossini GH, Ferreira EI. Nitric Oxide: State of the art in drug design. Curr Med Chem. 2012 Jan; 19(3): 386-405.

 • Naseem KM. The role of Nitric Oxide in cardiovascular diseases. Mol Aspects Med. 2005 Feb; 26(1-2): 33-65.

 • Iwata NG, Pham M, Rizzo N-O, Cheng AM, Maloney E, Kim F. Trans fatty acids induce vascular inflammation and reduce vascular Nitric Oxide production in endothelial cells. PLoS One.2011; 6(12): e29600.

 • Iachini Bellisarii F, Radico F, Muscente F, Horowitz J, De Caterina R. Nitrates and other Nitric Oxide donors in cardiology – Current positioning and perspectives. Cardiovascular Drugs Ther. 2011 Dec.

 • Toda N. Age-related changes in endothelial function and blood flow regulation. Pharmacol Ther. 2012 Feb; 133(2):159-76.

 • Castiglione N, Rinaldo S, Giardina G, Stelitano V, Cutruzzolà F. Nitrite and nitrite reductases : From molecular mechanisms to significance in human health and disease. Antioxid RedoxSignal. 2012 Feb. • Bescós R, Sureda A, Tur JA, Pons A. The effect of Nitric-Oxide-related supplements on human performance.Sports Med. 2012 Feb; 42(2): 99-117.

 • Kapil V, Milsom AB, Okorie M, Maleki-Toyserkani S, Akram F, Rehman F, Arghandawi S, Pearl V, Benjamin N,Loukogeorgakis S, Macallister R, Hobbs AJ, Webb AJ, Ahluwalia A. Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived N-O. Hypertension.2010 Aug; 56(2): 274-81.

 • Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, MacAllister R, Hobbs AJ, Ahluwalia A. Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension. 2008 Mar; 51(3): 784-90. 


• Guo LY, Hung TM, Bae KH, Shin EM, Zhou HY, Hong YN, Kang SS, Kim HP, Kim YS. Anti-inflammatory effects of schisandrin isolated from the fruit of Schisandra chinensis Baill. Eur J Pharmacol. 2008 Sep 4; 591(1-3): 293-9.

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